Clinical Knowledge Graph Explorer
AI-PoweredSarah Johnson
42F • MRN: 382947
AI Insights
Automatically extracted from clinical documentation
Key Insights for Cardiac Health
- Hypertension diagnosis (03/2024) shows correlation with increasing BMI trend over past 8 months
- Lisinopril therapy initiated 10/2024 correlates with 15% reduction in average systolic BP
- Stress echocardiogram (02/2025) showed mild left ventricular hypertrophy, correlating with long-standing hypertension
- Family history of premature CAD (father, MI at 52) increases 10-year ASCVD risk by 15%
Knowledge Graph Legend
Relationship Types
Interactive Knowledge Graph
Cardiac Health Focus • Last 12 Months
Hypertension
Essential (primary) hypertension (ICD-10: I10)
- Lisinopril 10mg daily
- Elevated BP readings (9)
- Mild LVH finding
AI-Generated Clinical Narrative
Automatically synthesized from knowledge graph connections
Sarah Johnson is a 42-year-old female with a history of hypertension diagnosed in March 2024. Her blood pressure has been consistently elevated with readings averaging 145/92 mmHg prior to treatment. She has a significant family history of premature coronary artery disease, with her father having had a myocardial infarction at age 52.
Treatment was initiated with Lisinopril 10mg daily in October 2024, resulting in improved but not fully controlled blood pressure, with recent readings averaging 135/85 mmHg. A stress echocardiogram performed in February 2025 showed mild left ventricular hypertrophy consistent with long-standing hypertension, but no evidence of ischemia.
Recent laboratory studies from March 2025 show normal renal function with a creatinine of 0.8 mg/dL and eGFR >60 mL/min. Lipid panel shows borderline elevation with total cholesterol of 212 mg/dL and LDL of 142 mg/dL. Lifestyle modifications including sodium restriction and regular exercise were recommended but patient notes indicate inconsistent adherence.
AI-generated narrative based on 134 document sources including 27 clinical notes, 12 imaging reports, and 43 lab results spanning 12 months.
AI Decision Support Insights
Medication Optimization
Current blood pressure control is suboptimal despite Lisinopril monotherapy. Knowledge graph analysis suggests potential benefit from:
- Increased Lisinopril dosage to 20mg daily, or
- Addition of thiazide diuretic (e.g., Hydrochlorothiazide 12.5mg)
Based on JNC 8 Guidelines and 3 similar patient cases with improved outcomes
Risk Factor Management
Knowledge graph identifies multiple modifiable risk factors contributing to 10-year ASCVD risk of 8.2%:
- Consider statin therapy (moderate intensity) for borderline elevated LDL
- Emphasize sodium restriction and DASH diet based on BP trends
- Document detailed family history of premature CAD
Based on ACC/AHA Prevention Guidelines and pattern recognition from structured data
Monitoring Recommendations
Based on clinical trajectory and knowledge graph projections:
- Repeat echocardiogram in 12-18 months to assess LVH progression
- Home BP monitoring 2x daily, with emphasis on documentation
- Consider 24-hour ambulatory BP monitoring to evaluate for masked hypertension
Based on pattern recognition from 26 similar clinical trajectories from knowledge base
AI decision support is generated from clinical knowledge graph analysis and pattern recognition across similar patient cases. These insights are designed to complement clinical judgment, not replace it.
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