Clinical Knowledge Graph Explorer

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Sarah Johnson

42F • MRN: 382947

134 Documents 27 Procedures 12 Imaging Studies 43 Lab Results

AI Insights

Automatically extracted from clinical documentation

Key Insights for Cardiac Health

  • Hypertension diagnosis (03/2024) shows correlation with increasing BMI trend over past 8 months
  • Lisinopril therapy initiated 10/2024 correlates with 15% reduction in average systolic BP
  • Stress echocardiogram (02/2025) showed mild left ventricular hypertrophy, correlating with long-standing hypertension
  • Family history of premature CAD (father, MI at 52) increases 10-year ASCVD risk by 15%
Evidence extracted from 27 clinical documents

Knowledge Graph Legend

Diagnoses
Medications
Vital Signs
Procedures
Lab Results
Clinical Notes

Relationship Types

Temporal (before/after)
Causal (caused by)
Treatment (treats)
Risk factor

Interactive Knowledge Graph

Cardiac Health Focus • Last 12 Months

Hypertension Lisinopril BP Readings

Hypertension

Diagnosis

Essential (primary) hypertension (ICD-10: I10)

Diagnosed: March 15, 2024
Source: Primary Care Visit (Dr. Chen)
Connected to:
  • Lisinopril 10mg daily
  • Elevated BP readings (9)
  • Mild LVH finding
Nodes: 47 Connections: 63 AI Confidence: 94%

AI-Generated Clinical Narrative

Automatically synthesized from knowledge graph connections

Sarah Johnson is a 42-year-old female with a history of hypertension diagnosed in March 2024. Her blood pressure has been consistently elevated with readings averaging 145/92 mmHg prior to treatment. She has a significant family history of premature coronary artery disease, with her father having had a myocardial infarction at age 52.

Treatment was initiated with Lisinopril 10mg daily in October 2024, resulting in improved but not fully controlled blood pressure, with recent readings averaging 135/85 mmHg. A stress echocardiogram performed in February 2025 showed mild left ventricular hypertrophy consistent with long-standing hypertension, but no evidence of ischemia.

Recent laboratory studies from March 2025 show normal renal function with a creatinine of 0.8 mg/dL and eGFR >60 mL/min. Lipid panel shows borderline elevation with total cholesterol of 212 mg/dL and LDL of 142 mg/dL. Lifestyle modifications including sodium restriction and regular exercise were recommended but patient notes indicate inconsistent adherence.

AI-generated narrative based on 134 document sources including 27 clinical notes, 12 imaging reports, and 43 lab results spanning 12 months.

AI Decision Support Insights

Medication Optimization

Current blood pressure control is suboptimal despite Lisinopril monotherapy. Knowledge graph analysis suggests potential benefit from:

  • Increased Lisinopril dosage to 20mg daily, or
  • Addition of thiazide diuretic (e.g., Hydrochlorothiazide 12.5mg)

Based on JNC 8 Guidelines and 3 similar patient cases with improved outcomes

Risk Factor Management

Knowledge graph identifies multiple modifiable risk factors contributing to 10-year ASCVD risk of 8.2%:

  • Consider statin therapy (moderate intensity) for borderline elevated LDL
  • Emphasize sodium restriction and DASH diet based on BP trends
  • Document detailed family history of premature CAD

Based on ACC/AHA Prevention Guidelines and pattern recognition from structured data

Monitoring Recommendations

Based on clinical trajectory and knowledge graph projections:

  • Repeat echocardiogram in 12-18 months to assess LVH progression
  • Home BP monitoring 2x daily, with emphasis on documentation
  • Consider 24-hour ambulatory BP monitoring to evaluate for masked hypertension

Based on pattern recognition from 26 similar clinical trajectories from knowledge base

AI decision support is generated from clinical knowledge graph analysis and pattern recognition across similar patient cases. These insights are designed to complement clinical judgment, not replace it.